Fenpropidin Property

Melting point:

25°C

Boiling point:

bp0.2 117°; bp0.045 125°; bp0.032 104°

Density 

0.9112 (rough estimate)

vapor pressure 

1.7 x 10^-2 Pa (25 °C)

refractive index 

1.4900 (estimate)

storage temp. 

Refrigerator

solubility 

Chloroform, Ethyl Acetate (Slightly)

pka

10.1

Water Solubility 

530 mg l^-1 (pH 7 at 25 °C)

color 

Clear Colourless

Merck 

13,4020

BRN 

5336091

CAS DataBase Reference

67306-00-7

NIST Chemistry Reference

Fenpropidin(67306-00-7)

EPA Substance Registry System

Piperidine, 1-[3-[4-(1,1-dimethylethyl)phenyl]-2-methylpropyl]- (67306-00-7)

Safety

Hazard Codes 

Xn

Risk Statements 

21/22-36

Safety Statements 

26-36/37

RIDADR 

2902

WGK Germany 

3

RTECS 

TM7292000

HazardClass 

6.1(b)

PackingGroup 

III

HS Code 

29333990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H317May cause an allergic skin reaction

H318Causes serious eye damage

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

Fenpropidin Chemical Properties,Usage,Production

Description

fenpropidine, a piperidine derivative, and spiroxamine, a dioxolanemethyleneamine derivative introduced in 1996 , belong to the same group of fungicides.

Uses

Fenpropidin is a fungicide.

Uses

Agricultural fungicide.

Uses

Fenpropidin is both a contact and a systemic fungicide which provides effective eradicant control of powdery mildew, rusts and leaf blotch in cereal.

Definition

ChEBI: A member of the class of piperidines that is N-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a p-tert-butylphenyl group.

Hazard

Moderately toxic by ingestion, inhalation, and skin contact.

Metabolic pathway

Limited data are available in the open literature. Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1993). Fenpropidin is stable to aqueous hydrolysis and photodegradation. Hydroxylation of the piperidine ring is the primary metabolic pathway in soil and wheat plants. Hydroxylation and oxidation of one of the methyl groups of the tert-butyl moiety are the major reactions in rats and lactating goats. The primary metabolic pathways of fenpropidin are presented in Scheme 1.

Degradation

Fenpropidin (1)i s stable to hydrolytic degradation (50 °C)in the pH range of 3-9 and when exposed to UV light in pH 5 buffer solution.